Spotlight Interviews

For Julio Medina, Founder and CEO of R2M Pharma, the main factor in choosing CDD Vault was the ease of implementation — how intuitive and easy the system is to use.

Thomas Sander heads the drug discovery informatics department at Idorsia Pharmaceuticals Ltd. and leads the team behind DataWarrior and the OpenMolecule platform. DataWarrior* and the OpenMolecule.org suite were created to provide an utilitarian platform of cheminformatics tools for synthetic and…

“We’re really pushing the boundaries looking for non-addictive pain medications and looking for ways to achieve that. Then on top of that, we’ve developed new ways to look at immuno-oncology and immunotherapy. Obviously this is an area that’s really at…

“I think that right now there seems to be a really big push into research on rare diseases. All the rare diseases are collectively getting together and saying, “Hey, we’re here!” – combined together they make one big common type…

“I wrote the book because…all drug discovery scientists have probably had a similar experience…people turn to you and they say “What do you do?”. And I say “Oh, well I’m in drug discovery”. And then people start asking you all…

CDD has teamed-up with iRND3 to help raise money for their efforts in Rare and Neglected Diseases.  For each customer referral, CDD will make a donation to iRND3, up to $10,000.  Current customers should simply email your recommendation to a…

“The other thing is, most of us scientists, we have some familiarity with computers, we use them all the time, we have smart phones, but we don’t want to know what’s going on behind the curtain computationally. We just want…

Going from academic research to industrial research, came with the realization that bulk data drives industrial research, whether its pharmaceuticals or agrochemicals. In academia you might focus in on a very specific issue and track data very carefully, on individual data points. In industry it’s all about bulk data, and it’s about drawing plots of multiple compounds vs multiple data points, and trying to find correlations and find the outliers and find the reason why compounds are doing what they’re doing. CDD Vault is a great tool for bulk data analysis…

“We’re using CDD Vault as a way of storing our chemical structures, as a way of searching them, as a way of storing all of our assay data. We’re also using it for doing calculations, for analyzing our data, for…

Interviewed by Collaborative Drug Discovery, Inc.
When you joined H3-D were they already using CDD Vault?

Yes, CDD Vault is a central database so everybody has access to the data. I have been with the project for 18 months now, and I run a dose-response inhibition assay which generates a significant amount of data analysis. I had intended to use GraphPad prism or Stata for my analysis in which I have to define controls and use a 4 parameter logistic regression for the curve generation. For large data sets, this takes a lot of time. I am a clinical research microbiologist, so I have a fair amount of experience with large datasets.

While uploading data to CDD, I noticed in the help section of CDD Vault that the platform has a customized 4-parameter logistic regression that is used to process and analyze the data. This has changed, a whole lot and for the better, the amount of time I need to upload and process the data. CDD Vault is not just a database to which I bulk upload data, but I actually use it to analyze and process all my data…