Collaborative Drug Discovery Database
industrial-strength software priced for academic laboratories
The CDD database enables scientists to archive, mine, and collaborate around pre-clinical chemical and biological drug discovery data through a web-based interface.
CDD helps distributed research groups to safely store and intelligently analyze their research data. Typical data include small molecule, enzyme, cell and animal bioactivity data accumulated from both low-throughput and high-throughput screens.
All you need is a web browser to get started instantly. There's nothing to install, maintain, or worry about backing up. Access your database from any Windows, Mac, or Linux computer through an intuitive web-interface that automatically hyperlinks disparate data together to reveal any type of structure-activity relationship (SAR). CDD trains and fully supports all users with superior service that we tailor appropriately to novice students or chem/bio-informatics experts.
Take a whirlwind tour — watch a three minute video to see what the CDD database can do. »
Archive experimental data in an easily searched database
- Import data easily - quickly and efficiently upload structured data (CSV, Excel, and SD/SDF files) or unstructured data (Word, JPEG, GIF, TIFF, PDF) into your group’s private database.
- Store data logically — the database understands typical enzyme, cell, and animal bioactivity data as well as PK/PD/ADME/Tox data.
- Customize your protocols — define preclinical SAR templates with any relationship or any other data type or view, even if you don’t know anything about programming or databases.
- Automate HTS data — CDD’s software maps and slurps up high-throughput enzyme inhibition and high content cell protocols.
- Organize data through an intuitive web-based interface — no database skills are needed, and you can also manually enter, edit and annotate data.
- Leave chemistry to the chemists and biology to the biologists — enter chemical structures and biological activity data separately if you wish; the results will correlate automatically via common structure names or other unique identifiers you specify.
- Start working right away — there’s nothing to install or “roll out”, just log in securely from any computer (Windows, Mac, Linux) and go.
- Relax — Your data is automatically encrypted and backed up securely and privately to multiple redundant sites hosted by CDD. There’s no hardware to maintain, no software to update, and no need to pay an IT specialist. CDD provides full customer support no matter how large or small your organization is.
Mine personal and public data collections to reveal new leads
- Search by chemical substructure, chemical similarity, keyword, or attribute — including bioactivity, potency and selectivity data, structure-activity relationships, pattern recognition, Boolean searches, modeling and more.
- Assess Lipinski's Rules and standard physical-chemical properties — calculated automatically for all compounds; CDD can also include custom models and algorithms as an additional service.
- Expand the scope of your searches to include open access and confidentially shared data — CDD currently hosts R&D data on FDA approved drugs, malaria, Chagas, and other neglected diseases; these collections are growing rapidly and can be customized around your targets and anti-targets.
- View, edit or compose chemical structures in 2D or 3D — ChemAxon’s Marvin Java applets are built-in to simplify structure-based searching.
- Visualize plate data — exploiting heatmaps and scatterplots for hit-to-lead identification, high-content screens, and multi-dimensional data.
- Exploit intelligent structure-aware tools — through an intuitive interface designed for ease of use by scientists and graduate students with little or no prior experience using sophisticated informatics tools.
Collaborate selectively by choosing what, when and with whom to share
- Maintain full control over your data — keep some or all of your data completely private, exchange data you specify confidentially with colleagues you authorize, or share openly with the global scientific community — you decide.
- Join existing communities organized around therapeutic or target areas — or build new private, semi-private, or open virtual drug discovery networks to accelerate your research and increase its impact.
- Export your data at any time to standard formats — we aren’t trying to lock you in to a proprietary system. You can also export chemical structure diagrams and calculated properties without the need for any additional software. Biologists especially like the ability to export structures and assay data to an Excel file with just two quick clicks.
- Share data directly through the web-based interface — invite selected colleagues to securely view subsets of data you specify through their web browsers.
- Time the release of data — hold and analyze data privately until a discovery is patented, published, or other restrictions lapse, then easily make the data available to selected collaborators or the global scientific community.