In this update we have changed the way numbers with modifiers (that is: >, <, ≥ and ≤) are aggregated. Numbers with modifiers are also referred to as bounded values, and this will mainly affect averages of IC50 measurements. The rule can be stated as: a bounded value will not be included when computing the average if there is another measurement that is consistent with it and is more specific. Exact values are always included.
- Less specific bounded values are not included: Average(<1, <10) = <1 Average(20, 30, <100) = 25 Average(80, <100, 150) = 115 (<100 is consistent with 80 and less specific)
- Bounded values are retained if they are not consistent with an exact value: Average(<2, 8) = <5
Other posts you might be interested in
View All Posts
CDD Vault Snack
5 min
July 28, 2025
Vault Snack #30 – Additional Curve Fits for Plotting and Analysing Assay Data in CDD Vault
Read More
CDD Vault Updates
2 min
July 24, 2025
CDD Vault Update (July #2 2025) Search Inventory by Molecule & Batch Fields, Protocol Plate Locations, Stoichiometry Table Debiting, Synonym Links in ELN, Chemical Properties in Structure Editor
Read More
CDD Blog
5 min
July 22, 2025
Drug Discovery Industry Roundup with Barry Bunin — July 22, 2025
Read More