News

  • CDD_Press_Release CDRD Chooses CDD for New Drug Discovery Informatics Platform February 11, 2016 - Press release BURLINGAME, CA and VANCOUVER, BC (February 11, 2016) — Collaborative Drug Discovery (CDD) today announced that The Centre for Drug Research and Development (CDRD) has chosen CDD Vault to replace their Drug Discovery Informatics Platform. After in-depth evaluation of leading systems, CDRD decided on the CDD Vault platform. CDD Vault is a hosted [...]
  • rollled_up_newspaper Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery published in PLOS Neglected Tropical Diseases June 26, 2015 - We are pleased to announce that the results of a phase I STTR collaborative study on Chagas Disease with groups at SRI International, UCSD, and UCSF have just been published in PLOS Neglected Tropical Diseases. Chagas disease is a neglected tropical disease caused by the eukaryotic parasite Trypanosoma cruzi. We used a combination of cheminformatics, bioinformatics, in vitro and in vivo testing to identify molecules active at eliminating the parasites from infected cells. We found that the European Medicines Agency approved antimalarial drug pyronaridine possessed 85.2% efficacy (reduction in parasite burden compared to untreated control group after 4 days treatment) in the acute Chagas mouse model and may represent a repurposing opportunity. This study also utilized the public T. cruzi datasets present in the CDD Vault. “This project demonstrates what can be achieved by combining complimentary approaches...
  • CDD_Press_Release CDD Awarded $1.5 Million Grant to Simplify Encoding of Bioassays with Automated Annotation Technology June 17, 2015 - Burlingame, Calif.—June 17, 2015—Collaborative Drug Discovery, provider of CDD Vault® web-based drug discovery informatics platform, announced they have been awarded a $1.5M Phase 2 SBIR grant to use the Bioassay Ontology Annotator as the foundation for a collaborative CDD ELN (Electronic Laboratory Notebook). The Bioassay Ontology Annotator software provided a strong proof-of-concept that one could use new automation technologies for comparison of assay conditions
  • CDD_Press_Release Introducing Eight New Chemical Libraries in CDD Vault June 24, 2014 - BURLINGAME, Calif. and Niagara-on-the-Lake, Canada — June 24, 2014 — Collaborative Drug Discovery (CDD) and Life Chemicals are proud to announce the availability of eight new chemical libraries in the CDD Vault software platform. These collections have over 370,000 original compounds selected for diversity and lead-like or drug-like properties. “We decided to highlight some of the [...]
  • rollled_up_newspaper Collaborative Drug Discovery (CDD) Announces Customer Advisory Board (CAB) Members May 27, 2014 - BURLINGAME, Calif. — May 27, 2014 — Collaborative Drug Discovery (CDD) is delighted to announce the members of our commercial Customer Advisory Board (CAB). The following industry thought leaders were carefully selected to help guide the short-term and long-term development of the CDD Vault platform: Jeff Blaney, Director Computational Chemistry & Chemoinformatics (Genentech) Henry Johnson, Senior Scientist (Amgen, Onyx Pharmaceuticals subsidiary) Thale Jarvis, VP Research & Development (Crestone Pharmaceuticals) Mark Gurney, CEO (Tetra Discovery Partners) Paul Humphries, VP Chemical Sciences (Reset Therapuetics) Daniel Erlanson, President (Carmot Therapeutics) As reported at the 10 Year Anniversary CDD User & Community Meeting, CDD Vault has the same number of user logins/month as a full year in 2008. CDD’s Product Manager, Kellan Gregory, commented...
  • rollled_up_newspaper Collaborative Drug Discovery Wins Phase II SBIR Grant to Develop Tools for Biocomputation across Distributed Private Data-sets to Enhance Drug Discovery November 19, 2013 - Burlingame, Calif.—Nov 19, 2013—Collaborative Drug Discovery (CDD), a provider of a web-based drug discovery informatics platform, announced they have been awarded a grant for a software development project focused on computational model and data sharing. The Phase II Small Business Innovation Research (SBIR) grant from the National Center for Advancing Translational Sciences is part of a program to enable sharing of biological data.
  • rollled_up_newspaper Cheaper and faster screening for antibacterials May 8, 2013 - BURLINGAME, Calif. — Scientists have collaborated to develop a way to reproducibly find promising molecules against the bacteria tuberculosis (TB) in silico, using off the shelf software. A team led by Sean Ekins at Collaborative Drug Discovery in Burlingame, CA with co-authors at the University of Medicine and Dentistry of New Jersey, Southern Research Institute, [...]
  • rollled_up_newspaper BIO5 Partners with Collaborative Drug Discovery to Manage Burgeoning Internal Compound Collection March 28, 2013 - BIO5 Partners with Collaborative Drug Discovery to Manage Burgeoning Internal Compound Collection   TUCSON, Ariz., March 28, 2013 — The University of Arizona’s BIO5 Institute Oro Valley (BIO5-OV) has partnered with Collaborative Drug Discovery (CDD), Inc. to use the CDD Vault, a state-of-the-art cloud technology, to capture and securely share BIO5’s drug discovery research data. [...]
  • ADC elements Informatics Considerations at the Dawn of the Antibody Drug Conjugate Era February 25, 2013 - Congratulations to Genentech/Roche-ImmunoGen on the FDA Approval of Kadcyla (Ado-Trastuzumab Emtansine), an Antibody-Drug Conjugate for Her2-Positive Metastatic Breast Cancer Antibody-Drug Conjugates (ADCs) combine the best of Nature’s capacity to rapidly evolve specificity with Science’s capacity to deliver specifically designed functionality. There are fascinating, unique ADC SAR (Structure Activity Relationship) informatics representation and optimization challenges when [...]
  • mike siani rose Michael Siani-Rose Brings Diverse Talents to CDD November 27, 2012 - Mr. Michael Siani-Rose brings his successful track record at Affymetrix, Chiron, Kosan, and Gryphon to CDD. Michael Siani-Rose (CDD Informatics) was most recently President of Cell Therapy Company Theregen.   Of particular relevance for CDD, with the emergence of Antibody Drug Conjugates and informatics standards such as HELM from big pharmas, Michael Siani-Rose co-published with SMILES [...]
  • mike travers Drug Discovery Informatics Veteran Joins CDD November 5, 2012 - Dr. Michael Travers brings a reproducible track record of commercially successful, informatics innovation to CDD’s strong technical team.   Dr. Travers’ broad bioinformatics and chemoinformatics experience adds an eclectic wind to CDD’s sail. Dr. Michael Travers (CDD Software Design) hails from SRI International’s Bioinformatics Research Group, where he worked on developing software tools to support [...]
  • TB CDD releases the first free mobile app for tuberculosis researchers: TB Mobile October 16, 2012 - Burlingame, Calif.—Oct 16, 2012—Collaborative Drug Discovery (CDD), a provider of a web-based collaborative drug discovery software platform, announced they have launched a mobile app for iOS that can assist tuberculosis drug discovery researchers...
  • Charlie Weatherall CDD Welcomes Charlie Weatherall to Scale Accounts Management September 28, 2012 - Press release   BURLINGAME, Calif., 27 Sept 2012 — Collaborative Drug Discovery (CDD) announces the addition of Charlie Weatherall to magnify CDD’s focus on its Community, further promoting the widespread acceptance of CDD’s platform among academic, government, biotech and pharma researchers. Prior to joining CDD, Charlie Weatherall worked with industry-leading scientific software companies such as MDL (dating [...]
  • CDD_Press_Release National Institute of Allergy and Infectious Diseases Awards Grant to Continue Development of Computational Tools for Tuberculosis Drug Discovery August 16, 2012 - The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded a second grant to Collaborative Drug Discovery, Inc. and SRI International to continue joint development of an information repository and software to identify novel therapeutics for tuberculosis (TB). The Phase II Small Business Technology Transfer Research (STTR) grant will support the next two years of research and focus on extending a systems biology-cheminformatics approach to develop molecular mimics and computationally evaluate them for drug efficacy.
  • CDD_Press_Release National Library of Medicine Awards Phase I SBIR Grant to Collaborative Drug Discovery, Inc. to Develop Computational Tools For Biocomputation across distributed private datasets to enhance drug discovery September 13, 2011 - BURLINGAME, Calif. Sept 13, 2011 — Collaborative Drug Discovery (CDD), a provider of a web-based drug discovery software platform, announced they have been awarded a grant for a software development project focused on ADME/Tox and tuberculosis drug discovery data sharing. The Phase I Small Business Innovation Research (SBIR) grant from the National Library of Medicine, [...]
  • CDD_Press_Release National Institute of Allergy and Infectious Diseases Awards Grant to SRI International and Collaborative Drug Discovery, Inc. to Develop Computational Tools March 28, 2011 - Menlo Park, Calif.—March 28, 2011—SRI International, an independent nonprofit research and development organization, and Collaborative Drug Discovery (CDD), provider of a web-based drug discovery software platform, announced that they have been awarded a grant to support the first year of a software development project focused on tuberculosis drug discovery efforts.
  • CDD_Press_Release CDD Provides Technology in Global Consortium to Identify New Tuberculosis Drugs March 4, 2011 - Burlingame, CA, March 4, 2011 — Collaborative Drug Discovery, Inc. (CDD; https://www.collaborativedrug.com/) has joined the École Polytechnique Fédérale de Lausanne (EPFL), AstraZeneca, Sanofi-Aventis, the Universities of Pavia, Uppsala and Cambridge, and nearly twenty other research groups from 13 different countries, to form the More Medicines for Tuberculosis (MM4TB; http://www.mm4tb.org/) consortium, which aims to develop new [...]
  • CDD_Press_Release Collaborative Drug Discovery, Inc. & Royal Society of Chemistry’s ChemSpider Announce Partnership February 25, 2011 - BURLINGAME, CA. and Wake Forest, N.C., February 21st, /PRNewswire/ — Collaborative Drug Discovery (CDD), the provider of the most widely used cloud-based drug discovery software platform on the market and Royal Society of Chemistry’s (RSC) ChemSpider, a leading provider of chemical services and data on the internet, have implemented two-way linking of public compounds that [...]
  • CDD_Press_Release Collaborative Drug Discovery Receives New Funding to Support Tuberculosis Drug Discovery Screening Efforts and Industrial-Academic Collaborations January 13, 2011 - BURLINGAME, Calif., Jan. 13, 2011 /PRNewswire/ — Collaborative Drug Discovery, Inc. (CDD) today announced that the Bill & Melinda Gates Foundation has extended its previous grant to CDD to create a novel database to spark collaborative efforts to discover more effective drugs against tuberculosis (TB). The TB bacillus infects approximately one third of the world’s [...]
  • cdd_public_data_chest_thumb Novartis Shares TB Data on CDD! September 17, 2010 - Novartis has made 283 compounds publicly available to the community. This is the first time a big pharma has released data on anti-tuberculosis compounds. Read more about the dataset and register here!